Synthetic Biologist

Posted on: 04 March 2022

Company Overview

Colorifix was founded by two synthetic biologists who were developing biological sensors to monitor heavy metal contamination in drinking water in rural Nepal.

While testing these sensors in Kathmandu,  Jim and Orr began to learn about the enormous impact of the dyeing industry on water and human health; and realised that,  rather than simply monitoring the problem,  they had the tools to solve it. With some creativity and a bit of luck,  Colorifix was founded in 2016.

Job openings

We seek to hire a highly motivated Synthetic Biologist to join the Microbial Engineering division at Colorifix as a Research Scientist. The successful candidate will be a pivotal member of the team, supporting the development of new pigment-producing strains, with a particular focus on creating, characterising and leveraging genetic tools.

Skills should include strong experience in synthetic biology / molecular microbiology, biochemistry, DNA assembly, genetic engineering, optimisation of metabolic pathways and genome engineering. Knowledge in fermentation, bioinformatics, enzyme engineering, automation or analytical chemistry would be advantageous but not essential. Candidates with a working knowledge of electronic notebooks and Good Manufacturing Practice (GMP) will be at an advantage, but training will also be provided. The Microbial Engineering team is looking for a candidate who enjoys multi-disciplinary teamwork, taking on challenges, shows creativity, flexibility, enthusiasm, and excellent communication skills.

Essential skills and experience

  • PhD in biological sciences or relevant work experience in a biological scientist discipline
  • Strong background and experience in synthetic biology: modular DNA assembly techniques, design and characterisation of genetic parts, metabolic pathway construction and optimisation, etc
  • Experience with CRISPR-Cas9 tools for genome engineering, CRISPRa and CRISPRi
  • Experience of working with and knowledge of the physiology of a range of chassis microorganisms including Gram-negative and/or Gram-positive and yeasts (e.g. Pichia pastoris and Saccharomyces cerevisiae)
  • Experience of metabolic engineering for enhanced small molecule production
  • Good communicator and flexible team player who is committed to the success of team as a whole
  • Passion for science together with a ‘can-do’ problem-solving approach
  • Good organisational skills with a high attention to detail
  • Respect for confidentiality and integrity

Desirable skills and experience

  • Experience with natural product biosynthesis.
  • Experience with protein engineering.
  • Experience with analytical chemistry techniques.
  • Experience of keeping a digital lab book.
  • Experience of working within a multi-disciplinary team.
  • Previous industry experience is desirable.

Title: Research Scientist
Reports to: Head of Microbial Engineering
Location: Norwich Research Park, Norwich
Remuneration: £37-42,000, depending on level of experience
Holidays: 25 + BH

Apply: Please submit your CV and cover letter to stating the role in the title

Colorifix is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.